It's... interesting. Played about 40 minutes last night. I may have skipped some important movie, but it feels like I'm missing a chunk of story. In the first 2 minutes of gameplay your character just decides to go of his meds and be a rebel? Oppressive government, missing/dead siblings, medication?
It's got the creepy edge of Bioshock 1, that feeling that the world around you is twisted in a bad way.
Plays a bit buggy though.
I'm interested to see where it goes, just don't know if I can give it much time...